Thinking of Multi-Cancer Early Detection (MCED) out of the box

Rivela diagnostics

Pioneers & specialists in Exosome biology

Rivela Diagnostics Ltd was established in 2022 to complete the R&D work in MCED started by its parent company Exosomics Inc, and to bring to the marketplace a propietary approach and assets on multi-cancer early detection. Exosomics and its subsidiary HansaBioMed Life Sciences, have lead the exosome space in Europe since 2011. Lonza has recently acquired Exosomics' business unit in Siena (Italy) to expand its exosome service offering worldwide and to strengthen Lonza's position as a leading global CDMO in exosomes bioprocessing. 

Based in the UK, RivelaDx Ltd will work with leading European research centres and industrial partners to bring to global markets a sustainable and reliable multi-cancer and pan-cancer testing approach.

Innovation and Revolution in Multi-Cancer Early Detection / Innovation and Revolution in Multi-Cancer Early Detection /
Management

Stephane Altaba

Chief Executive Officer

With nearly 30 years of experience in the healthcare industry, Stéphane Altaba is a seasoned professional. He earned an Engineering degree in Agronomy from ENSAIA, a PhD in biotechnology at INPL, and a business degree from ESCP-Europe. Following a post-doc at RIKEN in Japan, Stéphane dedicated over 12 years to various roles within the Sanofi Group, ranging from R&D to Industrial Affairs and Business Development. His final position at Sanofi was Group Licensing Director Oncology.

During his nine-year tenure at Nordic Pharma, Stéphane established strategic partnerships with pharmaceutical companies and orchestrated the creation of a subsidiary network in Europe to market the company's flagship products. He served also as General Manager of Nordic Italy for 4 years.

In 2015, he joined Genomic Vision, a molecular diagnostics company, where he served as Chief Operating Officer. Stéphane successfully reorganized the company, focusing on key markets such as diagnostics, bioproduction, and precision medicine, resulting in a significant boost in company development.

In 2020, Stéphane founded Strad Healthcare to offer consultancy services to Biotech and Medtech companies, assisting them in their commercial endeavors and the establishment of strategic partnerships. Concurrently, he assumed the role of CEO at LX Repair, a diagnostic company that developed a DNA repair assay to prevent radiotherapy side effects.

Antonio Chiesi

Chief Scientific Officer

Antonio Chiesi is the Founder and CEO of Exosomics Inc and HansaBioMed Ltd, both established to bring to commercial exploitation products for exosome research and exosome-based diagnostics emerging from his previous research at the Italian National Institute of Health (ISS) in Rome, where he acted as Head of Clinical Research for over 20 years. At the ISS, before leading intramural research in the exosome and cancer metabolism in the early years 2000, he led programs in Neuro HIV at a national level since 1990 and was engaged in several plans for early clinical development of anti-HIV drugs at EU Commission level. As a Startupper he raised over 10M euro from VCs and Industries (Lonza and Agilent) on Exosomics Inc up to the acquisition by Lonza of the business unit based in Siena, and brought to global commercial success HansaBioMed as the only and oldest exosome focused company. Currently he is engaged in Rivela Diagnostics, the new spin off of Exosomics Inc, aimed at bringing to the market a ground breaking approach to multi-cancer screening.

Antonio graduated as a Medical Doctor at the University of Roma La Sapienza in 1988 where he also got a Specialization in Neurology in 1992.  

Paolo Fabbrini

Chief Financial Officer

 - 30+ years as a Chartered Accountant
 - Deep experience in Administration and finance
 - Auditor of accounts in banks and companies
 - Expertise in mergers and acquisitions

Advisors

Pete Corish, PhD

Commercial Advisor

With 20 years of experience in core lab, Point-of-Care  immunoassay, and molecular diagnostics markets, Pete Corish has focused on commercialising R&D  and third-party innovative technologies in a number of Life Science and IVD businesses in the UK and US. This  has included applications for novel nanoparticle biolabels, DNA microarray analysis , genomic technologies for drug development, and new platforms for rapid, in-field diagnostics with digital connectivity. As the former CTO of BBI Solutions, a leading independent provider of IVD reagents, Pete was responsible for M&A, Commercial Strategic Partnerships and R&D, building out product and innovative technology portfolios. This is where he gained an initial interest in exosomes, and why he  recognises the world-leading experience of the Rivela team in exosome biology and the potential transformative impact on oncology, and other, diagnostics.

Natasa Zarovni, PhD

Scientific Advisor

Natasa Zarovni is a trained molecular biologist and physiologist with a PhD in Molecular Medicine from Open London University and University Vita Salute in Milan, and an over decade long academic research and project management experience in gene therapy, cancer immunology, stem cells, functional genomics. She has joined HansaBiomed and Exosomics as a member of the founding team and has worked as the R&D and Strategic Innovation Leader on building up the team, the IP portfolio, product pipeline and grants supported projects. Over last 13 years she has established herself as an “Exosome expert and enthusiast”, with excellent scientific and non-dilutive fund-raising track record. Through her active promotion and participation in over 20 collaborative projects, she has been supporting the growth of the overall EV Innovation and Research-to-Business ecosystem across EU.

Prof. Reinhard Zeidler

Scientific Advisor

Professor at the Klinikum der Universität München (KUM) and Group Leader at the Helmholtz Centre Munich.

Prof. Zeidler lab identifies new tractable target molecules specifically exposed on the surface of tumors and generates and characterizes corresponding first-in-class monoclonal antibodies for future clinical applications. The focus is on actually intracellular molecules that – for unknown reasons – are translocated to the plasma membrane of cancer cells rendering them accessible for targeted therapies.

Davide Zocco, PhD

Scientific Advisor

- Head of Exosome Development and Site Head at Lonza.

- 8 years Head of R&D at Exosomics Inc.

- Scientific leader reputation in exosome biology in the Biotech & Pharma industry

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